Survival-associated meQTLs across different cancer types
We identified 23,432 meQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
|
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
|---|---|---|---|---|---|---|---|---|---|
| CRC | rs11135614 | chr7:61096417 | A/G | 1.17E-6 | 369 | 10.27 | 20.27 | 24.15 | KM Plot |
| CRC | rs11135615 | chr7:61096641 | C/T | 7.7E-7 | 368 | 10.27 | 20.3 | 24.15 | KM Plot |
| CRC | rs11135616 | chr7:61096661 | T/A | 7.7E-7 | 368 | 10.27 | 20.3 | 24.15 | KM Plot |
| CRC | rs111519339 | chr7:62012968 | C/T | 7.1E-7 | 359 | 22.75 | 20.05 | 11.27 | KM Plot |
| CRC | rs111558487 | chr5:40863349 | C/T | 4.09E-5 | 372 | 22.37 | 21.43 | 26.1 | KM Plot |
| CRC | rs11173079 | chr12:59957833 | C/A | 1.09E-5 | 373 | 24.77 | 18.53 | 10.4 | KM Plot |
| CRC | rs11173083 | chr12:59967929 | T/C | 1.04E-5 | 374 | 10.4 | 18.13 | 24.77 | KM Plot |
| CRC | rs11173084 | chr12:59967980 | T/A | 1.04E-5 | 374 | 10.4 | 18.13 | 24.77 | KM Plot |
| CRC | rs11173085 | chr12:59968000 | G/A | 1.04E-5 | 374 | 10.4 | 18.13 | 24.77 | KM Plot |
| CRC | rs11173086 | chr12:59968015 | A/C | 1.04E-5 | 374 | 10.4 | 18.13 | 24.77 | KM Plot |
| CRC | rs11173087 | chr12:59968018 | C/G | 1.04E-5 | 374 | 10.4 | 18.13 | 24.77 | KM Plot |
| CRC | rs11189093 | chr10:99043689 | C/T | 3.33E-16 | 372 | 22.4 | 20.47 | 3.07 | KM Plot |
| CRC | rs11189094 | chr10:99043697 | T/C | 3.33E-16 | 372 | 22.4 | 20.47 | 3.07 | KM Plot |
| CRC | rs11196476 | chr10:115514581 | C/A | 2.48E-5 | 359 | 23.3 | 22.2 | 12.17 | KM Plot |
| CRC | rs112109844 | chr12:59966858 | C/CAT | 1.09E-5 | 373 | 24.85 | 18.13 | 10.4 | KM Plot |